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To examine the role of GSH precursor administration, NAC in the drinking water was given 4 hours after TNBS+ethanol administration and colonic tissue for evaluation of damage and GSH content was obtained at 24 hours post TNBS administration

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Vitvitsky V, Thomas M, Ghorpade A, Gendelman HE, Banerjee R: A functional transsulfuration pathway in the brain links to glutathione homeostasis